Our Pipeline

Precision-engineered regulatory T cell (Treg) therapies built for chronic nature of autoimmune disease.

Product
Indication
Discovery & Validation
IND Enabling
Clinical
Wholly-owned Programs
Phase 1/1b
Phase 2/3

SBT7101

Sonoma Solomark Fullcolor Rgb 72An autologous Treg therapy in development for rheumatoid arthritis (RA), engineered to activate at the site of disease.

SBT7101 is designed to recognize citrullinated protein, a marker present in inflamed tissue, directing the Treg to dampen local inflammation and restore immune balance without lymphodepleting conditioning.

We have initiated a Phase 1 study of SBT7101 in patients with poly-refractory rheumatoid arthritis. For more information, please visit ClinicalTrials.gov.

Partnered Programs

Treg Cell Therapeutics

Engineered Treg therapies for patients with Celiac Disease, inflammatory bowel disease, and other diseases, currently in preclinical development in partnership with Regeneron.

Wholly-owned Program

SBT7101

Sonoma Solomark Fullcolor Rgb 72An autologous Treg therapy in development for rheumatoid arthritis (RA), engineered to activate at the site of disease.

SBT7101 is designed to recognize citrullinated protein, a marker present in inflamed tissue, directing the Treg to dampen local inflammation and restore immune balance without lymphodepleting conditioning.

We have initiated a Phase 1 study of SBT7101 in patients with poly-refractory rheumatoid arthritis. For more information, please visit ClinicalTrials.gov.

Discovery & Validation
IND Enabling
Clinical
Phase 1/1b
Phase 2/3
Partnered Program

Treg Cell Therapeutics

Engineered Treg therapies for patients with Celiac Disease, inflammatory bowel disease, and other diseases, currently in preclinical development in partnership with Regeneron.

Discovery & Validation
IND Enabling
Clinical
Phase 1/1b
Phase 2/3
Partnered Program

Treg Cell Therapeutics

Engineered Treg therapies for patients with Celiac Disease, inflammatory bowel disease, and other diseases, currently in preclinical development in partnership with Regeneron.

Discovery & Validation
IND Enabling
Clinical
Phase 1/1b
Phase 2/3
Partnered Program

Treg Cell Therapeutics

Engineered Treg therapies for patients with Celiac Disease, inflammatory bowel disease, and other diseases, currently in preclinical development in partnership with Regeneron.

Discovery & Validation
IND Enabling
Clinical
Phase 1/1b
Phase 2/3
Istock 1189303727 Aspect Ratio 1559 1413

Partnerships

We collaborate with partners who bring complementary expertise to expand what’s possible for patients with autoimmune disease.